Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_936b4cec99b15a91cb86c9b1c6c8ca05 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00608 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00653 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00713 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G11C13-0069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G11C13-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G11C13-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B50-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B50-00 |
filingDate |
2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45a88370321f32655a978d2ec80dfca5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad78fd47b70f29f1e1431e172bf9414b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d839ae9877233c9391fa8e3b05c22bed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8338785d8f124c6c1d7fb93a12b175ec |
publicationDate |
2021-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021332351-A1 |
titleOfInvention |
Massively Parallel Enzymatic Synthesis of Nucleic Acid Strands |
abstract |
The invention is directed to methods for massively parallel template-free enzymatic synthesis of a plurality of different polynucleotides of predetermined sequences. In one aspect, methods of the invention employ large scale arrays of reaction sites each associated with at least one working electrode for controlling deprotection and deblocking steps at predetermined user selected sites. In another aspect, the invention provides template-free enzymatic synthesis with proofreading, wherein completed polynucleotides at predetermined reaction sites are sequenced using a sequencing by synthesis technique, particularly employing electrochemically labile blocking groups. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11515012-B1 |
priorityDate |
2018-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |