Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_110f336a70f725c0f1a5ac4401395ba8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate |
2021-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a146b98e6745d7eddf0fea202bf8d51d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_860a7e01ee1fd0011fa0eb9fa0f33101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a87e923bd05b408a18220e16584cd3e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff4cfb3a862d59e55c062da703f62cb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e33d49aeefe91433c778f0f2607bc011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e291ee4c5aa68b0af62ce20437330e8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be7482bbe745243fe52520f79eaa5d53 |
publicationDate |
2021-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021324387-A1 |
titleOfInvention |
Aav vectors for treatment of dominant retinitis pigmentosa |
abstract |
Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject. |
priorityDate |
2016-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |