| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ef293ff0b587a62911c8850e549254a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9ce2fc9e1a5c553fa815ac64ec46043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_545fc92c118c4653681008bf4db6de86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd001b0e366c01429ef1faaa8957dd4a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ab44549872ce2cec7aaed39208eb75a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b49740ab80834dc39c87b9bd38272af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9db15dc96772b1dd8f0cf355e02bb1ba |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2446-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2405-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-38 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate |
2019-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88955a02a1115b2f11e433b2afd6506b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a5a3b1ad0f8a17a3b1026c76d7324da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a8cdb966358cf7a93385d2c0ff8e793
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b8abfe8ff2a82d179e42c3935db268b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83ce636b2cf5c674609bf2a62373998b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca837069f9ae88109ecdf0fb36816474
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07dbf02daef4b6f915867e68a17035f2 |
| publicationDate |
2021-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021311049-A1 |
| titleOfInvention |
Rapid diagnostics of mycobacteria with lectin conjugated particles |
| abstract |
The present disclosure is generally directed to methods and systems for the rapid detection of mycobacteria in samples using lectin-conjugated silica coated magnetic nanoparticles (SMNPs). In this work, carbohydrates on the cell wall of the mycobacteria serve as binding sites for lectins conjugated on the surface of lectin-conjugated SMNPs. As the target species of mycobacteria bind to lectin-conjugated SMNPs, a precipitate forms, which can be magnetically separated from the bulk test solution to visually indicate the presence of the target species of mycobacteria. The present disclosure is utilized as an inexpensive and rapid point of care system in one embodiment. In another embodiment, the methods and systems are integrated into a lateral flow assay for rapid detection of the target species of mycobacteria. In yet another embodiment, the methods and systems are utilized to create a microfluidic detection device with increased sensitivity to mycobacteria in a sample. |
| priorityDate |
2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |