| abstract |
The present disclosure provides compounds represented by Formula I: n n n n n n n n n n wherein R 1a , R 1b , R 2a , R 2b , R 3a , R 3b , R 4 , A, L, X, Y, and Z are as defined as set forth in the specification. The present disclosure also provides compounds of Formula I for use to treat cancer or any other disease, condition, or disorder that is responsive to degradation of MDM2 protein. |