| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adb0e564374fedf34b36103d36e6455a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-00831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2017-0406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-06166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2207-068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D06M10-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01F6-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L23-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-148
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L17-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L23-06 |
| filingDate |
2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dc0c3d9f0d8716ea7fac5c8bd678c86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a65cd79d7022164c55b1596bfd9d2d0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74775b3e6ec73bccc5a83b7c0a441390
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d15ab9615f80d2281314ef1395094c96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ad93a656ac2d660e4a9b37a9e78944 |
| publicationDate |
2021-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021299332-A1 |
| titleOfInvention |
Osteoconductive fibers, medical implant comprising such osteoconductive fibers, and methods of making |
| abstract |
The disclosure relates to high-strength polyolefin composite fibers, which fibers have a fiber body comprising a composition consisting of polyolefin; 1-30 mass % of bioceramic particles having particle size D50 of 0.01-10 μm; at most 0.05 mass % of residual spin solvent; optionally 0-3 mass % of other additives; and wherein the sum of a)-d) is 100 mass %; and which fibers have bioceramic particles exposed at their surface, and show bioactivity. The composite fibers based on a composition of polyolefin with bioceramic particles mixed therein show particles being exposed at the fiber surface by techniques like AFM and XPS, and although apparently only a relatively small amount of bioceramic particles is exposed at the fiber surface, this appears sufficient for effective interaction with their environment and stimulating a positive biological response as demonstrated by in vitro cell studies.The present disclosure also concerns a method of making the high-strength composite fibers via a gel spinning process, fibrous articles comprising said bioactive composite fibers. Further embodiments concern use of these fibrous articles as a component of a medical implant or as a medical implant, especially as permanent high-strength orthopedic implants for repairing bone fractures or torn ligaments or tendons. Other embodiments include medical devices or implants comprising said fibrous articles. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11678923-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730866-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11491264-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11317957-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020392320-A1 |
| priorityDate |
2018-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |