| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6012ce2ccf64fbc34ba201c9f11ada92 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14034
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14251
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate |
2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7625c43c0b346db9a3ee861456e50f32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77003ddd715dc33bd9631662ca2b907c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48c8ea25794188784e04ca0923c5e5b6 |
| publicationDate |
2021-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021292371-A1 |
| titleOfInvention |
Stabilized filovirus glycoprotein trimers |
| abstract |
Filovirus glycoprotein mutations that stabilize the trimeric form of the glycoprotein are provided. The Filovirus glycoproteins have certain amino acid substitutions at specified positions in the glycoprotein sequence. The Filovirus glycoproteins described herein have an improved percentage of trimer formation and/or an improved trimer yield as compared to a Filovirus glycoprotein that does not have one or more of the indicated amino acid substitutions. Also provided are nucleic acid molecules and vectors encoding the Filovirus glycoproteins, as well as compositions containing the Filovirus glycoproteins, nucleic acid, and vectors. |
| priorityDate |
2018-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |