| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5db97a1c67e768f4b174d8c343d5a713 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01J49-168
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7266 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01J49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 |
| filingDate |
2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_797a1d1b9441133809634b3ef8a83edc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c1be70a3d3d1b2e16aaa3639923695a |
| publicationDate |
2021-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021285956-A1 |
| titleOfInvention |
The breaking of disulfide bonds of a nebulized analyte |
| abstract |
A method of ionising a sample is disclosed comprising nebulising a sample which includes first biomolecules such as bovine insulin comprising one or more disulphide (S—S) bonds. A stream of droplet or charged droplets comprising one or more disulphide (S—S) bonds is directed so as to impact upon a target ( 106 ) or electrode so as to cause the breaking of a portion of the disulphide bonds. Alternatively, charged droplets may pass through an electric field region determined by an electrode ( 106 ) arranged downstream of a nebuliser or electrospray probe and an ion inlet ( 104 ) of a mass spectrometer so as to cause the breaking of a portion of the disulphide bonds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021210322-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11621154-B2 |
| priorityDate |
2017-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |