| abstract |
A system and method for detecting in an eye, in particular the retina, of a mammal, tau protein, such as neurofibrillary tangles (NFT). The system and method can use fluorescence imaging in the visible or near-infrared spectral region, for example as a non-invasive method for in vivo imaging of tau protein in ocular tissue. In preferred embodiments, in vivo imaging of tau protein in ocular tissue involves tau-binding compounds such as FDDNP, T807 and T808. |