| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f734cf6f9668344fb7af4edbf73b6593 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001112 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
2021-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1577ea724130b8164345206f6fb3a748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_427e8593ca72ffdcd71a3b09edf8ec57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdded801ee9f405bd80da130fe51864f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e5b7cc415b9f99235eb3d9a6391ed17 |
| publicationDate |
2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021275586-A1 |
| titleOfInvention |
Use of a car cell having crosslinked disulfide bridge on antigen recognizing moiety for targetting cancer cells |
| abstract |
The invention is directed to the use or a method of using of a cell expressing a chimeric antigen recognition structure (CAR) bound to an adapter molecule, wherein:n i) the CAR structure comprisesn a) an antigen binding domain specific for the tag of the adapter molecule, b) a transmembrane domain c) an intracellular domain wherein the n ii) the adapter molecule comprisesn a) a tag which is specific for the antigen binding domain of the CAR structure b) a polypeptide comprising an antigen recognizing domain specific for an antigen expressed on the target cell, wherein the polypeptide comprises a heavy chain and a light chain connected by a sulphur atom-linker-sulphur atom bridge and wherein the linker is covalently bound to a single tag n for targeting target cells, especially human tumor cells. |
| priorityDate |
2020-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |