| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3a501c55088061cf130ae8894f348ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec7de8c519d0c8aae413fafd44bd2358
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b28cc4dff22c39966f55eedc1106a4c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b1f4845003539abb6a368cbe21a3f27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_053291de2192a78e711a5574d9ec8313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2234a12b2f1bb060af0756e3c26eaa1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf4831d18f397680eb49b020ca883ddb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate |
2021-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08707e8940aaeb310391d2c333a296be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0eb591c7482b923055d7edd9872ea41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d3a287b949f833f00b27aab9d4f076c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c37ab2e6a75b659c5e37f507b61308cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_936bf9a78d63fb37ba9ab803f1755061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_424c8f36b976306f3100472a63200389 |
| publicationDate |
2021-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021275464-A1 |
| titleOfInvention |
Biomembrane-covered nanoparticles (bionps) for delivering active agents to stem cells |
| abstract |
The present invention provides bio-nanoparticles (BioNPs) for delivering an active agent into hematopoietic stem & progenitor cells (HSPCs). Each BioNP comprises a core and a biological membrane covering the core, which comprises the active agent and a polymer. The biological membrane comprises a phospholipid bilayer and one or more surface proteins of a megakaryocyte (Mk). The active agent remains active after being delivered into the HSPC. Also provided are methods for preparing the BioNPs and uses of the BioNPs for targeted delivery of an active agent into HSPCs and/or treating or preventing a disease or condition in a subject in need thereof. |
| priorityDate |
2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |