http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021269801-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60da379fb33c192ef77f86a60c5ac029 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate | 2019-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_950ea9223e81389fa398fbec09403a53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac6adfb93eef916804491f3b6135b209 |
publicationDate | 2021-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2021269801-A1 |
titleOfInvention | Methods of Managing Nucleic Acid Replication, Expression, and Cleavage Using CRISPR Associated Nucleases |
abstract | This disclosure relates to methods of using a guide RNA sequence and CRISPR associated (Cas) nucleases for the purpose of managing replication of nucleic acids or expression of genes associated therewith. In certain embodiments, methods further optionally contemplate cleaving the nucleic acids at desired target sequences. Although it is not intended that certain embodiments of this disclosure be limited by any particular mechanism, is believed that shortening a guide sequence to partially hybridize with a target template strand prevents a guide RNA and Cas nuclease complex from catalyzing the cleavage of the nucleic acids and represses RNA transcription or protein expression. |
priorityDate | 2018-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 325.