Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e75810cb7d022e16fc3e012a68ae090 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 |
filingDate |
2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a9157cf87fae036b7a309767751208d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c9d225a64c64fdcddb2731c1f691cd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3de1513a565731a221c2a19ffb7211a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d32b4cbcd61cdb650182afa9b7a82676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_677708e739c1a30409203f49db40be05 |
publicationDate |
2021-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021254156-A1 |
titleOfInvention |
Growth Differentiation Factor 15 as Biomarker for Metformin |
abstract |
The present invention relates to metformin for use in treating a patient, wherein the patient exhibits an increased level of GDF15 in response to metformin treatment; to methods of identifying a patient who will benefit or who will not benefit from metformin treatment; methods of treating a patient at risk of developing or suffering from a disease or disorder comprising administering therapeutically effective amount of metformin; methods of adapting the dosage of metformin; the usage of GDF15 as biomarker for identifying a patient who will benefit or who will not benefit from metformin treatment, kits for use in identifying a patient who will benefit from metformin treatment and the use of the kits, as well as methods of treating a patient or who will not benefit from metformin treatment. |
priorityDate |
2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |