abstract |
The present invention relates to a compound comprising an antibody or a fragment thereof operable to transmigrate across the blood-brain barrier (BBB), and a polypeptide related to the treatment of lysosomal storage disease (LSD), for the treatment of α-synucleinopathies, or both. The present invention also relates to pharmaceutical compositions and methods for 5 treating LSDs, treating, α-synucleinopathies, or both. |