http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021252071-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d452ebbe234b18c80d0462dc24578da3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
| filingDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_360a5bc1397d1003812216976f5517a4 |
| publicationDate | 2021-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2021252071-A1 |
| titleOfInvention | Method for cartilage repair and pre-osteoarthritis treatment |
| abstract | Methods and compositions comprising an isolated in vitro pre-conditioned population of placenta derived mesenchymal stem cells (PMSCs), wherein the PMSCs promote de novo regeneration of cartilage when the PMSCs are administered to a subject. A method of treating one of osteoarthritis, cartilage damage or loss, and pre-osteoarthritis in a patient comprising administering to the patient a pharmaceutical composition comprising an isolated in vitro pre-conditioned population of placenta derived mesenchymal stem cells (PMSCs), wherein the in vitro pre-conditioning comprises providing a population of mesenchymal stem cells from a placenta, and culturing the population of mesenchymal stem cells in a medium comprising soluble Notch ligand Jagged1 (JAG1); and a pharmaceutically acceptable carrier. A pharmaceutical composition comprising placenta derived mesenchymal stem cells (PMSCs), Notch ligand Jagged1 (JAG1), and a pharmaceutically acceptable carrier. |
| priorityDate | 2020-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 331.