Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ee0da6543d4d16f0634e75baf2d0d58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate |
2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3149c495364aaf7ea8b3aea48e650aca |
publicationDate |
2021-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021244822-A1 |
titleOfInvention |
Conjugates with internal and terminal-end heparosan linkages |
abstract |
Described herein are compositions such as antibody-drug conjugates that include a heparosan polymer. In some embodiments, a targeting moiety is bound to an end of the heparosan polymer or to an internal monomeric subunit of the heparosan polymer. In some embodiments, a payload molecule is bound to an end of the heparosan or to an internal monomeric subunit. Some embodiments relate to methods of making and using the compositions. |
priorityDate |
2018-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |