| abstract |
The present invention refers to a composition comprising a conditioned cell culture medium obtained or obtainable by a process which comprises culturing a population of mesenchymal stromal cells (MSCs), in which at least about 25%, at least about 30%, at least about 35%, at least about 40%, at least about 45%, at least about 50%, at least about 55%, at least about 60%, at least about 65%, at least about 70%, at least about 75%, at least about 80%, at least about 85%, at least about 90%, at least about 95%, at least about 96%, at least about 97%, at least about 98%, or at least about 99%, of said population by number of cells are MSCs obtained from a mammal pertaining to the genus Canis , in a nutrient rich liquid prepared for cell culture, preferably a basal media; and collecting the conditioned cell culture medium, wherein preferably the nutrient rich liquid is an animal/human serum-free media or a chemically defined animal/human serum-free and xeno free media designed to grow MSCs, for use in therapy. |