Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95e7278486e9ba6a3c0365c6c302909f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6832 |
filingDate |
2019-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb5fa1e1e8833b4d487b23bc01876c24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5779369102d6a99d3bdd271edaeb1e9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c6dd8a6bb2a2b3d6e9d00fd71354f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a1c49c62f7736de5ad16c870fca067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86e8106eb4ff55bacab9b8cb3b8e0b5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d11a9e23c204402b24f081a6fafb955 |
publicationDate |
2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021230680-A1 |
titleOfInvention |
Modified Nucleobases with Uniform H-Bonding Interactions, Homo- and Hetero-Basepair Bias, and Mismatch Discrimination |
abstract |
Described herein are divalent nucleobases that each binds two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone, such as in a γ-peptide nucleic acid (γPNA). Also provided are genetic recognition reagents comprising one or more of the divalent nucleobases and a nucleic acid or nucleic acid analog backbone, such as a γPNA backbone. Uses for the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided. |
priorityDate |
2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |