| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1264bdf8494e865eebe23dba8808caef |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 |
| filingDate |
2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a1c486db19e915cd3bf8c1674621072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52b60bf49ea0a3d17b5f8722cb981171
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b2b6d95b3f3acc96ae1efb7d5acfba2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d01991ff1e4509c3f35e5da53885f669
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_110efc59985ed109091c88754d7c578b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c96f1e169a914c8d32728be56c57971
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a19a7840b6cc98610761c23355c4987f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_660d6873229dd836554d0f842588e691
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e55584a93ee39539536361d9702f04 |
| publicationDate |
2021-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021230655-A1 |
| titleOfInvention |
Demethylation of Reticuline and Derivatives Thereof with Fungal Cytochrome P450 |
| abstract |
The invention relates to recombinant host cells that expresses one or more genes encoding a cytochrome P450 enzyme capable of N-demethylating and/O-demethylating reticuline and/or derivatives thereof, and also methods of producing a N-demethylated and/or O-demethylated reticuline and/or derivatives thereof, comprising cultivating the recombinant host of the invention in a culture medium under conditions in which the one or more genes encoding the cytochrome P450 enzymes is/are expressed. The reticuline and derivatives thereof are useful for providing access to naturally unavailable and chemically difficult-to-produce starting materials for opioids. |
| priorityDate |
2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |