| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab93c7850d906ce03998a938e7bdc0af |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 |
| filingDate |
2020-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f22dbbdc83115b40a6e063e55bcb5cbe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d6f7d4b134eebc86f1e78810b4bea3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c8db102e916116ae24db5f1156fbfdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5529cab655134b1012792d4b3c7a742
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_912eba6f9b99ef6482a38212eb051a5a |
| publicationDate |
2021-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021222203-A1 |
| titleOfInvention |
Rxr-alpha gene knockout cell line with stable and low rxr-alpha protein expression and production method thereof |
| abstract |
The present invention relates to the technical field of biological preparation, and particularly to a RXRα gene knockout cell line with stable and low RXRα protein expression. The cell line is a RXRα gene knockout cell line, in which non-3 integer multiple of bases are knocked out. The RXRα protein expression in the cells is significantly decreased and the genotype is stable to be passaged, thus greatly improving the stability of the cell line with low RXRα protein expression. This is conducive to the stable passage and continuous culture of the cell line. The present invention further provides a production method of the cell line. |
| priorityDate |
2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |