Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-206 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2021-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa472fc4343773e2d2e73a9498bed6d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac3fab67c50d75dcba0eace700e2724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_081646ab15f949bc88603968d69fdd81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_734c18a161439ab3b463c05a681bbea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c4e94678b16c618e128b5ff65916574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6cb99bc9a8d0871836ad8b20831229c |
publicationDate |
2021-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021220489-A1 |
titleOfInvention |
Amygdalar neural ensemble that encodes the unpleasantness of pain |
abstract |
An ensemble of neurons in the basolateral amygdala (BLA) has been identified that encodes nociceptive information across pain modalities, including pain evoked by noxious thermal and mechanical stimuli. Methods are provided for screening candidate agents for inhibition of neural activity of the BLA nociceptive ensemble. Screening assays further include determining the effectiveness of candidate agents in alleviating pain and reducing aversive pain avoidance behavior. |
priorityDate |
2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |