abstract |
A method and a composition for treating TRPV1-mediated diseases based on a growth differentiation factor 11 (GDF11) peptide is disclosed. Since the method or composition for treating pain using inhibition of TRPV1 activity of the present invention exhibits an excellent effect of suppressing neuropathic pain caused by spinal nerve damage, it can be used as a novel pain therapeutic way for various pain conditions and diseases related to the TRPV1 channel such as arthritis and diabetic peripheral neuropathy. In addition, since it effectively inhibits TRPV1 activity, it can be utilized as a therapeutic way for treating various TRPV1-mediated diseases. |