Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ef5610592b44f6fb5e89f764a1acdb3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-0241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate |
2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02b7165af28243d0861ca2a1923ba2b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1349c0b7d9301e93b8d10b57778dc9b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9848d516d1e4132a7a2cbf193eec7950 |
publicationDate |
2021-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021214493-A1 |
titleOfInvention |
Antimicrobial polycarbonates for multidrug resistant bacteria |
abstract |
Compositions and methods regarding guanidinium functionalized polycarbonates that provide potent antimicrobial activity against multidrug resistant (MDR) bacteria, including Klebsiella pneumoniae ( K. pneumoniae ) are provided. According to an embodiment, an antimicrobial guanidinium-functionalized polymer is provided that comprises a hydrophobic molecular backbone with cationic guanidinium moieties respectively bound to the hydrophobic molecular backbone via butyl spacer groups. The antimicrobial guanidinium-functionalized polymer self-assembles into a micelle structure with hydrophobic residuals of the antimicrobial guanidinium-functionalized polymer buried inside the micelle structure and the cationic guanidinium moieties exposed on an external surface of the micelle structure to target pathogens. |
priorityDate |
2018-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |