http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021198663-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3189130addfe7f682e5cfaa0a5fe9a7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2aefb16f9a2c934dfd5ea7120eb50990 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4742 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fe3de0c1fcb56b5021491abbfee2df2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8d3d4abacbe216e119e94d03f826fab |
| publicationDate | 2021-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2021198663-A1 |
| titleOfInvention | Nanowires/Microscale Pyramids (NWs/MPs) Complex Structure, Method for manufacturing the Same and Its Applications to Isolation of Circulating tumor cells (CTCs) and Detection of Epstein-Barr virus (EBV) DNA |
| abstract | A nanowires/microscale pyramids (NWs/MPs) substrate complex structure is formed with a plurality of pyramids. Each triangular surface of the pyramid is formed with nanowires to increase the contact area. In one application, anti-epithelial-cell adhesion-molecule (anti-EpCAM) antibodies are modified on the nanowires. The anti-EpCAM antibodies serve to capture circulating tumor cells (CTCs) in blood for determining whether the cancer cells have metastasized to other organs. In another application, the nanowires are modified with silver nanoparticles (AgNPs) which can be combined with other functional groups for testing. The AgNPs on the NWs/MPs substrate causes the NWs/MPs substrate to become a substrate with surface enhanced Raman scattering (SERS). The AgNPs are bound with Epstein-Barr virus (EBV) probe DNA which can be hybridized with EBV target DNAs so as to determine the concentration of the EBV target DNAs in blood. The methods for fabricating the substrate and its applications are also provided. |
| priorityDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.