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filingDate 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2021189471-A1
titleOfInvention Molecular beacon-based optical gene biosensor employing retro-reflection and quantitative analysis method of nucleic acid molecule
abstract An optical gene biosensor is disclosed. The optical gene biosensor includes a substrate; a molecular beacon anchored to the substrate, wherein the molecular beacon includes an oligonucleotide specifically binding to a target nucleic acid molecule and a first compound bound to a first terminal of the oligonucleotide; an optical marker specifically binding to the first compound, wherein the optical marker is configured to retro-reflect irradiated light; a light source for irradiating the optical marker with light; and a light-receiver for receiving light retro-reflected from the optical marker. The optical gene biosensor may perform accurate quantitative analysis of a target nucleic acid molecule using both non-spectral and spectral light sources.
priorityDate 2017-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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