| abstract |
The compounds of the invention as shown by general structure I, as shown below, are effective in treating filovirus infections. n n n n n n n n n n n n X is selected from the group consisting of O and H; n R 1 is selected from (C 6 to C 10 ) aryl and (C 2 to C 9 ) heteroaryl, and n R 2 is selected from (C 1 to C 10 ) alkyl, (C 1 to C 10 ) alkenyl, (C 1 to C 10 ) alkynyl, (C 3 to C 10 ) cycloalkyl, and (C 5 to C 10 ) cycloalkenyl, and n NR 3a R 3b is defined in the specification. n n n n n These compounds are effective in treating filovirii infections including Ebolavirus and Marburg virus. |