| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4f6fc524bbaefe59b7dd499f2d11b4ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13043 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 |
| filingDate |
2019-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06e432214be187cfa40dee88fab7e6c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd82189d74c314db1a04bc1d17057af9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_324dfa83b7ddedb1a45b8c92987e281f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f95a6987cce9d0f84e454b70fbb6d14 |
| publicationDate |
2021-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021155941-A1 |
| titleOfInvention |
Compositions and methods for making engineered t cells |
| abstract |
The disclosure provides a vector which can be used in a method of generating engineered T cells for use in an autologous or allogeneic setting for engineered immunotherapy. The knockdown of endogenous TCR expression through a vector comprising a miRNA cassette allows for engineering of cells that efficiently express a therapeutic TCR. |
| priorityDate |
2018-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |