| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a99dc04afeaf6c3e8e43069d0636a62b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate |
2020-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae38641085809c2aeb1526aa8b107ce4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db1710c2b8d6cffecd726645abc18447
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85555b32409374fab312616779b841f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c9f923fb264f4a34a27db5cba5931e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_992317d8242e04f70986d7196668e671
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7d42ed691b56f07fa88335b9c389514 |
| publicationDate |
2021-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021154198-A1 |
| titleOfInvention |
Combination therapy involving diaryl macrocyclic compounds |
| abstract |
The present disclosure relates to methods and compositions for treating cancer with a diaryl macrocycle in combination with an inhibitor of MAPK/ERK kinase-1 and -2 (MEK1 and MEK2; MAP2K1 and MAP2K2), such as trametinib. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023031925-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023178262-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023108110-A3 |
| priorityDate |
2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |