http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021147820-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e74277852f1aae0a3ff13f59a65456d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-04 |
filingDate | 2020-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46f6af595449506c2c50c6bd495382d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fb2c57c2b38135122939e4fbdbea428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb490cdf9375cce7ea5320a93242c2b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee2083896dbca41946bc4b7869d14bfe |
publicationDate | 2021-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2021147820-A1 |
titleOfInvention | Diels-alderase and use thereof |
abstract | The present invention provides a Diels-Alderase and use thereof, and belongs to the field of gene engineering technology. The Diels-Alderase is MaDA, and its amino acid sequence and gene sequence are represented by SEQ ID Nos. 1 and 2, respectively. The present invention also provides MaDA-1 and MaDA-2, both of which are homologous proteins of MaDA, and their amino acid sequences are represented by SEQ ID Nos. 10 and 12, respectively. The present invention has discovered that MaDA and its homologous proteins from Morus alba can stereospecifically synthesize natural products of endo configuration, and prepare D-A type natural products and their analogs in vitro using chalcones and dehydroprenyl-containing compounds as substrates, which helps to develop and utilize the medicinal value of such natural products, and also provides a possibility to synthesize other six-membered ring-containing important chemical precursors or natural products. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113943716-A |
priorityDate | 2019-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 253.