http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021139845-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_465b607edb4c88aeefb4958e154efaec |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57536 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-073 |
| filingDate | 2019-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f579124048bb75c1cc0ab01902240bbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f23e6201071238cbd273ff295d8890c |
| publicationDate | 2021-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2021139845-A1 |
| titleOfInvention | Composition for promoting efficiency of somatic cell replication |
| abstract | The present invention relates to a composition for promoting the efficiency of somatic cell replication, comprising endothelin as an active ingredient. When somatic cells are treated with the composition of the present invention, H3K9me3, which is suspected to be a factor for the lowering success rate of nuclear substitution, is inhibited, and H3K4me3, which has the opposite effect, is increased to increase the success rate of nuclear substitution. Accordingly, the composition of the present invention increases the efficiency of somatic cell replication, thereby increasing the efficiency of producing pluripotent stem cells derived from nuclear substitution, and ultimately, the composition is expected to contribute to the development of cell therapeutic agents. |
| priorityDate | 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.