Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1331de48d5d73b7d08e681ebd78c9b04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45bdc8c376a952fb8392876ed772b2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18fc37cd9e18049af854ada351f054b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bedecaa07f0b7ccb1eaca25f2c1ecd87 |
publicationDate |
2021-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2021137931-A1 |
titleOfInvention |
Selecting patients for therapy with adenosine signaling inhibitors |
abstract |
Described herein are measures of the relative expression levels, within a given sample from a subject, of an ACPP transmembrane splice variant to the expression level of one or more ACPP non-transmembrane splice variant(s). The measures, designated ρ, show correlation with clinical outcome for the subject. In some cases, values of ρ exceeding a predetermined cutoff can be associated with poorer outcomes. Methods of determining ρ and assigning the predetermined cutoff value are described. Methods of treating cancer are also described. |
priorityDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |