http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021130769-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2537-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0006 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
filingDate | 2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b945d183ba72791b1db601b2a76b378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30675df114db8a7c3793943ad83dfe90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_172412628f5718917e69098f6d0be58f |
publicationDate | 2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2021130769-A1 |
titleOfInvention | Method for Single Cell Encapsulation via Metabolic Glycoengineering and Copper-Free Click Chemistry |
abstract | A method of single-cell encapsulation of cells using glycoengineering and click-chemistry is provided. Cells are treated with a precursor for metabolic engineering to modify glycans in a cell membrane and form reactive component A-glycans in the cell membrane suitable for a click-chemistry reaction. The treated cells are suspended in a polymer solution which has a reactive component B suitable for the click-chemistry reaction. The reactive component A-glycans react via the click-chemistry with the reaction component B thereby forming single cell polymer encapsulated cells. Applications include optimizing stem cell function, cell to cell crosslinking, formation of networks of cells or organoids, functionalizing the cells with reactive groups or attaching the cells to a substrate or surface. |
priorityDate | 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 274.