| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60442fdc20fd71481fc3d6b8cdee2c31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N63-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 |
| filingDate |
2018-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_837f776083e7f9d8fd8ad3a0f7883214
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ef9e63f03cb6790caed57b561830565 |
| publicationDate |
2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021130417-A1 |
| titleOfInvention |
Systems and methods for designing synthetic antimicrobial peptides |
| abstract |
Methods for generating synthetic antimicrobial peptides include (i) identifying a peptide fragment of an antimicrobial peptide that includes a cluster of cationic residues and at least about 25% hydrophobic residues, preferably between about 40%-60% hydrophobic residues and (ii) generating a peptide variant library based on the peptide fragment by varying a hydrophobicity and charge of residues that make up the peptide fragment. Resulting synthetic peptides can include linear synthetic peptide variants of an AS-48-like bacteriocin having increased antimicrobial activity. |
| priorityDate |
2017-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |