abstract |
This invention relates to compositions and methods relating a combination of naturally-occurring active ingredients, including active agents unrelated to statins, useful for the regulation total blood cholesterol. The inventive combination of active ingredients, including policosanol, mevinolic acid from dry yeast extract of red rice, dry extract of Lespedeza captitata, and dry grape seed extract, interrupts or inhibits the metabolic pathway leading to biosynthesis of cholesterol and cholesterol ester at multiple points and may also reduce high triglyceride levels. The present invention may be used to achieve normal blood serum LDL cholesterol concentrations and establish a healthy balance between LDL and HDL, all while significantly reducing the risk of statin-related side effects. |