| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd24d0edc441a277cf5d128b2c97b31 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H10-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06N20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H50-20 |
| filingDate |
2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad0cb84139a4a40559a5d37e9e77782
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f686b6d094a6f32575ccf42a37850e67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3a614c1e9377874e58d1b1f061eb82a |
| publicationDate |
2021-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021104297-A1 |
| titleOfInvention |
Systems and methods for determining tumor fraction in cell-free nucleic acid |
| abstract |
Systems and methods are disclosed for determining tumor fraction in cell-free nucleic acid of a liquid biological sample of a subject. Sequence reads are obtained using the biological sample. The sequence reads are used to identify support for each variant in a variant set thereby determining an observed frequency of each variant in the variant set. For each respective variant in the variant set, a corresponding reference frequency for the respective variant is obtained in a reference set, where each corresponding reference frequency in the reference set is for a respective variant in an aberrant solid tissue sample obtained from the subject. The observed frequency of each respective variant in the variant set is evaluated against the observed frequency of the respective variant in the reference set thereby determining the tumor fraction in cell-free nucleic acid of the liquid biological sample. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4138003-A1 |
| priorityDate |
2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |