| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-735
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
2020-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597ffcf813d8124cd9ab1c1bf23e0caf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_779a3e858909094c6753e34224ebf25d |
| publicationDate |
2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021079073-A1 |
| titleOfInvention |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy |
| abstract |
The present invention provides compositions and methods for regulating the specificity and activity of T cells. In one embodiment, the invention provides a type of chimeric antigen receptor (CAR) wherein the CAR is termed a “KIR-CAR” which is a CAR design comprising a component of a receptor naturally found on natural killer (NK) cells. In one embodiment, the NK receptor includes but is not limited to a naturally occurring activating and inhibitory receptor of NK cells known as a killer cell immunoglobulin-like receptor (KIR). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11149076-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11608382-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11549099-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11747346-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11667691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11591404-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11578130-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535662-B2 |
| priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |