| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_835284fef6d8becc0032b30b06c99d24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c617b8d542b722cc6adebad9df4506d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ed597501d55e1e6dc653a6628a8c813 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
| filingDate |
2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccd73143549abeba84982cc611010ed9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60a7d25cbf7a98e07d9cc4ea79496de0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d2a86c83fff5524d4082dc12feac0d |
| publicationDate |
2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2021071317-A1 |
| titleOfInvention |
Combinatorial derivatives of rna oligonucleotides |
| abstract |
The essence of the invention Combinatorial derivatives of RNA oligonucleotides, wherein for their production, covalent modification of the initial RNA oligonucleotides is carried out by simultaneous combinatorial carboxylation and formylation of the exocyclic amino groups of adenine, guanine, cytosine and the ribose alcohol residue in the reaction with the maximum number of different synthesis derivatives, and as a result of synthesis, a combinatorial mixture of derivatives of each oligonucleotide is formed and then use the resulting combinatorial mixture as a whole without fragmentation to create biologically active compositions. |
| priorityDate |
2017-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |