http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021070719-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbf39c5519ede057f3dc9a73f2d85ac2
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-36
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-36
filingDate 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_252962be143bc40098a7de7b22b0aebd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e617f13679fd0b97e011291e5996795
publicationDate 2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2021070719-A1
titleOfInvention Synthesis of 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-thiazole
abstract The present invention provides an improved process for preparing 5-chloro-2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-thiazole comprising reacting 2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-thiazole with N-chlorosuccinimide (NCS) in the presence of water, the improvement comprising performing the step of reacting the compound of formula (II) with NCS in the presence of a reduced amount of water. The present invention provides an improved process for preparing 5-chloro-2-[(3, 4,4-trifluoro-3-buten-1-yl)thio]-thiazole comprising reacting 2-[(3, 4,4-trifluoro-3-buten-1-yl)thio]-thiazole with N-chlorosuccinimide (NCS) in the presence of water, the improvement comprising performing the step of reacting the compound of formula (II) with an excess molar amount of NCS.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352335-B2
priorityDate 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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