http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021047307-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5456846495c5fa8a02f5eaae9faae290 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-58 |
| filingDate | 2020-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_805acf89985fe64217f361e2560ec08d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c32437ae1223a98c6ebcb64ffad7de8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbbefca6510259792270efded7f58abb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57db97790c8322e55b251845cc168057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_359821b5685e6d26db804c3c06d058a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d6801acf5901f4e58afad830c3b383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62900bf60811feb71b9234c991fff07c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e254613029e197ee8300aa7bfc490fb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0683ee4a19ed62891698dc5063029b7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0de7e3f22af46417bc5730161698503a |
| publicationDate | 2021-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2021047307-A1 |
| titleOfInvention | Andrographolide compound and method for treatment or prevention of fibrotic disease using the same |
| abstract | A compound represented by formula I or II. R 1 and R 2 are at each occurrence selected from the group consisting of hydrogen, methyl, phenyl, 2-methoxyphenyl, 3-methoxyphenyl, 4-methoxyphenyl, 3,4,5-trimethoxyphenyl, 2-hydroxyphenyl, 3-hydroxyphenyl, 4-hydroxyphenyl, 2-fluorophenyl, 2-chlorophenyl, 2-bromophenyl, 3-fluorophenyl, 3-chlorophenyl, 3-bromophenyl, 4-fluorophenyl, 4-chlorophenyl, 4-bromophenyl, 2-fluoro-3-methoxyphenyl, 3-methoxy-4-chlorophenyl, 2,4-difluorophenyl, 2,4-dichlorophenyl, 2,4-dibromophenyl, 2-fluoro-4-chlorophenyl, 2-bromo-4-chlorophenyl, 3-fluoro-4-chlorophenyl, 3-bromo-4-chlorophenyl, 3,4-difluorophenyl, 3,4-dichlorophenyl, 3,4-dibromophenyl, 2-chloro-4-fluorophenyl, 2-bromo-4-fluorophenyl, 3-chloro-4-fluorophenyl, 3-bromo-4-fluorophenyl, 2-fluoro-4-bromophenyl, 2-chloro-4-bromobenzene group, 3-fluoro-4-bromophenyl, 3-chloro-4-bromophenyl, 2,3,4-trichlorophenyl, 2-methoxy-4-chlorophenyl, 2-hydroxy-4-chlorophenyl, 2-hydroxy-4-methoxyphenyl, 3-fluoro-4-(4-methylpiperazinyl)phenyl, 4-(N,N-dimethylamino)phenyl, and 3-fluoro-4-(4-morpholinyl)phenyl. R 3 and R 4 are hydrogen, or R 3 and R 4 are at each occurrence selected from the group consisting of —CH 2 CH 2 COOH, —CH 2 CH 2 CH 2 CH 2 COOH, —CH 2 CH═CHCH 2 COOH, and —CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 COOH; or R 3 and R 4 are —COR 5 , and R 5 is selected from the group consisting of 3-pyridyl, —CH 2 CH 2 COOH, —CH 2 CH 2 CH 2 CH 2 COOH, —CH 2 CH═CHCH 2 COOH, and —CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 COOH. |
| priorityDate | 2018-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.