| abstract |
Disclosed are means, methods and treatments of Leigh Syndrome, using mesenchymal stem cells. In one particular embodiment, mesenchymal stem cells are administered for the purposes of reducing disease progression, and reversing disease. Said mesenchymal stem cells may be generated according to the invention, by selection of markers specifically upregulated or downregulated on enhanced cells as compared to majority of mesenchymal stem cells. The invention further provides means of co-administration of mesenchymal stem cells with lysates, conditioned media, or exosomes of said mesenchymal stem cells to enhance therapeutic activity. |