abstract |
An amide derivative inhibitor and a preparation method and an application thereof are provided. Specifically, a compound shown in general formula (I), a preparation method for same, a pharmaceutical composition containing the compound, and an application of same as an ASK inhibitor are provided. The disclosed compounds can be used for the treatment of neurodegenerative diseases, cardiovascular diseases, inflammation, autoimmune and metabolic diseases. Each of the substituents in the general formula (I) is as defined in the description. |