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filingDate 2020-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88ba1828ceb4a0a2de46761af5b6572f
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publicationDate 2021-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2021015874-A1
titleOfInvention Use of bio-transformed bear bile powder in preparation of anti-inflammatory drugs
abstract A use of bio-transformed bear bile powder in preparation of anti-inflammatory drugs is disclosed. The present invention carries out a comparative research on the anti-inflammatory drug activity of bio-transformed bear bile powder and natural bear bile powder. A research is made on the effect of the bio-transformed bear bile powder and natural bear bile powder on carrageenan-induced rat inflammation models, and a research is made on the effect of the bio-transformed bear bile powder on LPS-induced lung inflammation in mice. Experimental results show that the bio-transformed bear bile powder administration group obviously reduces plantar swelling of carrageenan-induced inflammation model in rats, and the effect thereof is not lower than that of the natural bear bile powder. Both the bio-transformed bear bile powder and the natural bear bile powder can significantly reduce levels of the inflammatory factors IL-6 and TNF-α in the lung and the serum.
priorityDate 2019-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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