http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021008015-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47f38f98e2d5dd32c9da7f4b21d065c5 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0a83a87f84d7050085d46a0e2dc14c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4db3818579ed6a3c406008895eb352c8 |
publicationDate | 2021-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2021008015-A1 |
titleOfInvention | Hepatoprotectent phenylbutyratyrate drug conjugates, and their compositions preparation and methods of use thereof |
abstract | In this current invention our primary aim to provide a phenylbutyrate conjugates and composition suitable for oral, or parenteral administration which overcomes the abovementioned problems. Phenylbutyrate conjugates are provided, which have a phenylbutyrate moiety covalently linked to a second drug such as Acetaminophen, or other drug molecules which induced hepatotoxicity. A compound for use in the treatment or prevention of a disease selected from hepatotoxicity, drug induced hepatotoxicity, or liver necrosis, and nonalcoholic steatohepatitis (NASH), and treat Pain, fever, cancer, inflammation, a composition for the treatment of ischemic injury or nerve damage in a human or animal, the compound having a structure selected from: **F-I** Formula and Formula **F-II* or anhydride, or pharmaceutically acceptable salt solvate thereof. It is one or more compounds or pharmaceutically acceptable salt or composition comprising a solvate of the foregoing. |
priorityDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 124.