Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd698bacfaf52f81addc4a2bd0261a6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3114ad1e84b3265d6e7db82296faf7b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B60R1-066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B60R1-072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-0212 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B60R16-023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 |
filingDate |
2017-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6d6b03f39e3270276e5613691cc1b03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0994b421819445ef1d024d82185b6a3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe2a1e585f8ae0c7d1749dace94f4d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d635e7ac3d12ce4470e5fab470374bab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbb5856e0e6dfb300c4335635b53807b |
publicationDate |
2020-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020405612-A1 |
titleOfInvention |
Human growth hormone fusion protein with enhanced thermal stability and cosmetic composition for anti-wrinkle and maintaining skin elasticity comprising the same as effective component |
abstract |
A human growth hormone fusion protein has enhanced thermal stability. The human growth hormone fusion protein has the amino acid sequence SEQ ID NO: 3 or SEQ ID NO: 4. A gene encoding the human growth hormone fusion protein has E. coli codon-optimized nucleotide sequence of SEQ ID NO: 5 or SEQ ID NO: 6. A recombinant vector includes the aforementioned gene. A host cell is transformed with the aforementioned recombinant vector. A method for producing in a host cell a human growth hormone fusion protein includes transforming a host cell with the aforementioned recombinant vector. The human growth hormone fusion protein may improve skin wrinkle and maintain skin elasticity. As the human growth hormone fusion protein has thermal stability and also has an effect of improving skin wrinkle and increasing the effect of maintaining skin elasticity, it can be advantageously used as a raw material of cosmetics. |
priorityDate |
2016-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |