| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d58c3fab3867279bd2c6afdfb5bf4b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0457
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0631 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502753
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D63-088 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D63-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
| filingDate |
2018-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc2655771c6fca56ada0f6b25dcff5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4f133c070a5a445c6777adf2fc26439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e08e777bc94f6a9b4d550987bab9098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24ac3cba8dd8f1b735ba4e1d2aaa001d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fa95f277bc202a6acd9df77eba41c24 |
| publicationDate |
2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020393450-A1 |
| titleOfInvention |
Detection device for bioluminescent detection of biomarkers from a biological fluid sample using luminescent sensing proteins |
| abstract |
A fully integrated Òsample-in-signal-out Ó microfluidic paper-based analytical devices are provided relying on bioluminescence resonance energy transfer (BRET) switches for target analyte recognition and colorimetric signal generation. Simultaneous colorimetric detection and quantification of multiple antibodies in a single drop of whole blood is shown. The devices make use of BRET-based antibody sensing proteins integrated into vertically assembled layers of functionalized porous layer(s) of material. The device enables sample volume independent, eliminates addition of reagents to the sample, and has on-device blood plasma separation. User operation is a single drop of a sample and the acquisition of a photograph after sample introduction, with no requirement for precise pipetting, liquid handling or analytical equipment except for a camera. Using different antibodies as targets, simultaneous detection in whole blood was achieved. This device is believed to be ideally suited for user-friendly point-of-care-testing in low-resource environments based on BRET-sensors. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023135444-A1 |
| priorityDate |
2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |