| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3155069b833b184bcd4ad12f7100dd4c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2535-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0657 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 |
| filingDate |
2020-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9697700e4405461dedc14f1e54469743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afad0224bf5f7c9769c1a48a79852800
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_087752bf80f6ceed709a779d5b3c4558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e06b1bffcbb88564ec1515909a4d0429 |
| publicationDate |
2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020362314-A1 |
| titleOfInvention |
Methods to produce adult-like cardiomyocytes derived from induced pluripotent stem cells for drug discovery |
| abstract |
Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are a powerful tool for studying cardiovascular disease and drug screening. However, most current methods of cell culture result in cells resembling fetal myocardium, which is potentially problematic as most forms of cardiovascular disease occur in the adult heart. Disclosed systems and methods include culturing cells in fatty-acid based medium and on patterned growth to produce hiPSC-CMs which mimic adult cardiomyocytes and display a similar hypertrophic response as is observed in cardiovascular disease. |
| priorityDate |
2019-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |