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filingDate 2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f4fae3435da6f2b2e18a59054755a7
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publicationDate 2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2020362014-A1
titleOfInvention Applications of soluble protein baff in b cell in-vitro culture and proliferation
abstract Disclosed in the present invention is an application of soluble protein BAFF in B cell in-vitro culture and proliferation. Peptide expressed by secretory BAFF peptide in the present invention can be effectively secreted out of cells to generate corresponding bioactivity. During the process of culture, a cell line in the present invention can continuously secrete water-soluble BAFF protein having bioactivity, the water-soluble BAFF protein served as tool cells are co-cultured with B cells, and in-vitro proliferation and antigen presentation effects of human B cells can be effectively improved.
priorityDate 2016-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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