| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d58c3d1d07d46f8cc92af20bd9fa5ac3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-944
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1767
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-465 |
| filingDate |
2019-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_372022a4386f7e121ac76a5cd5f1e47b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ef8bf93a93b633bd45bc25b29bc3596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3a6fae537fb0dcf347bb52c22e3ad70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6014a757c25f73a5c2b757430dc7a4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9198ff55b82b8b3fc0941b4d714848da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34f12bbc6713270212171edcc17ca18d |
| publicationDate |
2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020360364-A1 |
| titleOfInvention |
Methods and compositions for treating inflammatory or autoimmune diseases or conditions using chrna6 activators |
| abstract |
The present invention provides methods for treating inflammatory or autoimmune diseases or conditions using activators tin of nicotinic acetylcholine receptors (nAChRs) containing a cholinergic receptor nicotinic alpha 6 subunit (nAChRαS), such as activating antibodies that bind to a nAChR containing a nAChPα6 subunit and small molecule agonists of nAChRs containing a nAChRαS subunit. The invention also features compositions containing α6*nAChR activators, methods of diagnosing patients with an α6*nAChR-associated inflammatory or autoimmune disease or condition, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with α6*nAChR activators. |
| priorityDate |
2018-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |