http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020354707-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54a8d71b502ac0d93ac7cfdce2dc142e |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24007 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-52 |
filingDate | 2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16290d5694723a2c824a7df446383977 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e67582e752741a0e2cf14cc8b5df3faa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eddb9d5313f3b3ee6e968dbd44597e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8a7a0f290933fef1c4befb1f33e89e |
publicationDate | 2020-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2020354707-A1 |
titleOfInvention | Process for the production and purification of the collagenase enzyme from vibrio alginolyticus |
abstract | The present invention claims a novel process for the production and purification of microbial collagenase (Microbial Collagenase EC 3.4.24.3) produced by the non-pathogenic aerobic bacterium Vibrio alginolyticus chemovar. iophagus (NCIMB Number: 11038, synonym LMG 3418, hereinafter called Vibrio alginolyticus ), which said process provides high production levels of collagenase with a stable, reproducible, cheap fermentation process. The collagenase produced from Vibrio alginolyticus according to the process described herein also presents a specific activity superior to that of other microbial collagenases, is stable in aqueous solution, and can be frozen without significant damage. A further subject of the present invention is pharmaceutical compositions containing collagenase obtained according to the production and purification process described, for the purpose of therapeutic treatment of disorders characterised by collagen accumulation or for the treatment of blemishes/imperfections that benefit from reducing local collagen accumulations. |
priorityDate | 2012-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.