Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87a863132c68cf0f62015bbd5d05ab38 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2318-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-39 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate |
2020-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4afd9c707c7a6d3f5bc9b8050b75cb4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f542c86c742b8a7ad24d60fd33a929db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e70f55f766ae1234d05106bf72a37ef2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a593a82525c86c6439699cd90894bd52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8249e9302de890ac0484645882d269f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94584350883ffc2adea9d87984844f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_151fc1d014c9083bf24cb69accc00c37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4ca730c0714ddce8eaff712a74604db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a52ccdaddb3ddb986c03c18e9454ab48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dafd90f4e103ad1a933fb216f4e7f56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc904d43fe6cf53939c4a430338cd4b9 |
publicationDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2020325210-A1 |
titleOfInvention |
Cysteine engineered fibronectin type iii domain binding molecules |
abstract |
Cysteine engineered monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules comprising one or more free cysteine amino acids are prepared by mutagenizing a nucleic acid sequence of a parent molecule and replacing one or more amino acid residues by cysteine to encode the cysteine engineered FN3 domain containing monospecific or bispecific molecules; expressing the cysteine engineered FN3 domain containing molecules; and recovering the cysteine engineered FN3 domain containing molecule. Isolated cysteine engineered monospecific or bispecific FN3 domain containing molecules may be covalently attached to a detection label or a drug moiety and used therapeutically. |
priorityDate |
2016-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |