| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4db6a6055213164d2cb8a05b66c05dde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66c1d8c7b56ecc040aa15d34df5277b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_06e343b40e742b0387fcb56945eb4162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d746005412c3c6d2924a2b3dba638b8e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate |
2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f39c8001e7afda65b6cea1d1dfa3177
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44a9fb51bc2939348400889d116250ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcd06309f7c28012c3a96e22802997d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f1d91a1f2fcbef7683e9f38dc446b7a |
| publicationDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2020325190-A1 |
| titleOfInvention |
Modification and Compositions of Human Secretoglobin Proteins |
| abstract |
Novel compositions of recombinant human CC10 protein have been generated by chemically modifying the pure protein in vitro. Several new synthetic preparations containing isoforms of chemically modified rhCC10 have been generated by processes that utilize reactive oxygen species and reactive nitrogen species. These preparations contain novel isoforms of rhCC10 which have been characterized with enhanced or altered biological properties compared to the unmodified protein. Preparations containing novel isoforms may be used as standards to identify and characterize naturally occurring isoforms of native CC10 protein from blood or urine and ultimately to measure new CC10-based biomarkers to assess patient disease status. These preparations may also be used to treat respiratory, autoimmune, inflammatory, and other medical conditions that are not effectively treated with the unmodified protein. |
| priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |